We can help you with your concerns. Charlotte Charlotte is the largest city and financial center in North Carolina (about 900,000 residents in 2020). Charlotte is located in southwestern North Carolina. Charlotte was named for Queen Charlotte of King George III of England. Also, Charlotte has the nickname "The Queen City". Charlotte is characterized by the following. Economic Center: Charlotte is a financial center, home to the headquarters of many Fortune 500 companies, including Bank of America and Duke Energy. Charlotte also has a thriving economy in technology, healthcare, and manufacturing. Sports: Charlotte is a major sports city, home to ...