We can help you with your concerns. Kernersville Kernersville is a town between Winston-Salem and Greensboro. The location of Kernersville is closer to Winston-Salem. In addition, there is a high point south of Kernersville. Kernersville is located in Forsyth County in the Piedmont Triad region. Kernersville has the following characteristics. History: Kernersville was established primarily as a trading center due to its convenient location between the aforementioned major cities. Originally called "Dobson's Crossroads" or "Kerners Crossroads," the name was later changed to Kernersville in 1873 in honor of Joseph Kerner, a prominent resident. Economy: Historically, Kernersville's economy was based on ...