We can help you with your concerns. Murphy Murphy is the town with the county seat of "Cherokee County" in westernmost North Carolina. Murphy is also famous for its casino! Located in the Appalachian Mountains, Murphy is known for its scenic beauty, outdoor recreational activities, and relaxed small town atmosphere. Murphy is characterized by the following. Natural Beauty: Murphy is surrounded by picturesque scenery including lush forests, rolling hills, and water features such as the Hiwassee River and the Appalachian Trail. Outdoor Activities: Outdoor enthusiasts will find plenty to do in and around Murphy. Activities such as hiking, fishing, boating, ...