We can help you with your concerns. You can learn from us. Winston-Salem Winston-Salem is a twin city in north-central North Carolina. Here are the main nicknames for Winston-Salem and why Winston-Salem is an amazing city! Twin City: Because Salem, founded in 1766, and Winston, founded in 1849, merged in 1913.Camel City: Because of the city's historical involvement with the tobacco industry in connection with R. J. Reynolds Tobacco Company's "Camel" cigarettes, which are headquartered in Winston-Salem.Easter City: Because Moravian Easter Sunrise Service has been held in Salem for more than 200 years. Winston-Salem is also a vibrant city located ...